Structural Biology (ER-C-3)

At the ER-C-3, we use a comprehensive electron microscopy approach to study the biological structures of membrane-associated protein complexes. Our main methods of investigation are single-particle electron cryo-microscopy (cryo-EM) as well electron cryo-tomography (cryo-ET) that we are also developing to advance existing imaging technologies towards high-resolution structural biology.

Head: Prof. Carsten Sachse

Carsten Sachse; Simon Fromm; Stefan Huber, ©Carsten Sachse, Forschungszentrum Juelich 2021

Research

We use an integrated structural electron microscopy approach to study the biological structures of membrane-associated protein complexes.

Ralf-Uwe Limbach, ©Carsten Sachse, Forschungszentrum Juelich 2021

Instrumentation

Electron cryo-microscopy (cryo-EM) is an integral part of the Ernst-Ruska Centre with world-leading equipment in ultra-high resolution electron microscopy.

©Carsten Sachse, Forschungszentrum Juelich 2021

Publications

Selected publications

©Daniel Mann and Carsten Sachse, Forschungszentrum Juelich 2021

Personal lab page

For more detailed information on our research projects including latest news and complete list of publications, please visit our personal lab site.