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Institute of Bio- and Geosciences
Biotechnology (IBG-1)

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New mass spectrometric method for the separation of 13C and 15N-labelled amino acids
Isotope-based methods have been established for many years in biotechnological and medical research for the detailed investigation of cell metabolism. For the quantitative determination of intracellular metabolic fluxes, 13C-based metabolic flux analysis has become a routine method. In this model-based procedure, the relative fractions of enriched 13C isotopes in intracellular metabolites (so-called isotopologues) form the essential data basis. The latter can be measured using highly sensitive mass spectrometric methods.
to announcement: New mass spectrometric method for the separation of 13C and 15N-labelled amino acids …

Our Mission: White Biotechnology


IBG-1 – an interdisciplinary team

Biologists, biochemists, chemists, computer scientists, physicists, and engineers form an interdisciplinary team with a common aim: the use of microorganisms or isolated enzymes for the synthesis of bio-products from renewable carbon sources.

Exploiting the natural capabilities of microorganisms

For thousands of years mankind has employed the metabolism of microorganisms, e.g. for the making of bread, cheese, wine, or beer. However, the enormous potential of microorganisms and enzymes for the synthesis of new bio-products, such as basic or fine chemicals, pharmaceuticals and proteins, from renewables is still not exploited to a large extent.

Sustainable products and processes

Research at IBG-1 aims at a detailed molecular understanding of microorganisms and enzymes which are used as biocatalysts and includes approaches of systems biology and synthetic biology. The resulting knowledge and technologies are used for the development of novel resource-efficient and sustainable bio-processes, thereby reducing our dependency on fossil carbon sources, in particular crude oil.