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Institute of Neuroscience and Medicine

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Working groups

Architecture and Brain Function

The working group „Architecture and Brain Function“ develops a three-dimensional atlas of the human brain, which reflects the intersubject variability in brain organization. Central element is the regionally specific distribution of nerve cells, i.e., cytoarchitecture.

Big Data Analytics

The creation of models and atlases of the human brain with high-resolution 3D image datasets poses enormous challenges to image processing methods and algorithms, as well as data and workflow management. The working group develops solutions to these challenges.

Fiber Architecture

The working group „Fiber Architecture“ develops the microscope technique 3D-Polarized Light Imaging (3D-PLI) in terms of hardware design, HPC based images analysis, and fiber modelling and measurement simulation. The goal is to reconstruct nerve fibers and their pathways in 3D at the micrometer scale.

Genomic Imaging

The working group „Genomic Imaging“ aims at demonstrating the structural and/or functional changes caused by genetic variants in the brain and how they contribute to the development of neuropsychiatric and neurodegenerative diseases.


The working group „Connectivity“ deals with the importance of fiber tracts for the structure and architecture of the surface and cortex of the brain. A particular focus is the alteration of surface and fiber tract anatomy in older age.

Neuroanatomy of Language

The group “Neuroanatomy of Language” conducts systematic analyses of the relationship of brain structure and function. For this purpose, methods from theoretical linguistics, empirical psycholinguistics, clinical neurolinguistics, genetics, neuroimaging (MRI, fMRI, MEG), and neurostimulation (TMS, tDCS) are combined.

Clinical Neuroanatomy

Exploring movement disorders. Only if and when the performance of our movements is disturbed, we do realize how much in life depends on the precise execution of movements