Bioprocesses and Bioanalytics

About

The research activities of the Bioprocesses and Bioanalytics group are focused on the characterization and optimization of microbial bioprocesses, applying bioprocess and metabolic engineering principles including aspects of downstream processing and metabolic modeling. A key technology is the development and application of laboratory automation platforms for acceleration of microbial strain characterization, bioprocess optimization and molecular biology workflows.

Research Topics

- Metabolic and bioprocess engineering for high and low molecular weight products

- Laboratory automation tools for acceleration of molecular biology workflows and bioprocess development

- Tools to speed strain characterization and bioprocess developent by microscale cultivation, lab automation and digitalization

- Modeling and machine-learning tools for improved decision-making and autonomous microcultivation experiments

- Scale-down bioreactor approaches addressing scale-up and scale-down research topics

Contact

Prof. Dr. Marco Oldiges

IBG-1

Building 15.4 / Room 256

+49 2461/61-3951

E-Mail

Bioprocesses and Bioanalytics

Members

Prof. Dr. Marco OldigesHead of Bioprocesses and BioanalyticsBuilding 15.4 / Room R 256+49 2461/61-3951

Scientific staff

Dr.-Ing. Bertram GeinitzScientific staffBuilding 15.4 / Room 253+49 2461/61-3941
Vanessa SchmittScientific AssistantBuilding 15.4 / Room 252+49 2461/61-3374

Technicians

Petra GeilenkirchenTechnicianBuilding 15.4 / Room R 252+49 2461/61-3954
Matthias MochTechnicianBuilding 15.4 / Room R 253+49 2461/61-3941

PhD students

Michael OsthegePh.D. studentBuilding 15.4 / Room 136+49 2461/61-8646
Lisa PrigolovkinPh.D. studentBuilding 15.4 / Room 305+49 2461/61-3475
Katja RohrPh.D. studentBuilding 15.4 / Room 257+49 2461/61-3962
Christian WagnerPh.D. studentBuilding 15.4 / Room 252+49 2461/61-3374

Students

Bo KernMaster studentBuilding 15.4 / Room 264+49 2461/61-3958
Josefin SanderMaster studentBuilding 15.4 / Room 254+49 2461/61-2611
Rabea SchruffStudentBuilding 15.4 / Room 254+49 2461/61-2611
Katharina SchwartzBachelor studentBuilding 15.4 / Room 254+49 2461/61-2611

Research

Current activities concentrate on production systems for low and high molecular weight products (e.g. amino acids, organic acids, antibiotics, ketoacids, lipases, proteases, etc) utilizing pro- and eukaryotic microbial systems, such as Corynebacterium glutamicum, Bacillus subtilis, Pichia pastoris, Bacillus licheniformis, Eschericha coli, Gluconobacter oxydans, Penicillium sp. and Saccharomyces cerevisiae. Besides routine applications of parallel bioreactor setups for bioprocess development the group operates a pilot plant facility (300 L scale) for scale-up approaches. In addition, we have developed a medium throughput cultivation platform making use of a microtiterplate cultivation platform which can be operated in combination with a liquid handling robotic system for significantly increased cultivation throughput.

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Last Modified: 30.04.2024